Timolol is a prescription drug, belongs to a class of medication known as a “non-selective beta-adrenergic receptor antagonist”. In ophthalmic form, it is used to treat glaucoma. It works by decreasing the amount of fluid within the eye, whether or not accompanied by glaucoma.

What is Timolol Ophthalmic drops used for?

It is used to treat elevated pressure inside the eye such as in ocular hypertension and glaucoma (open angle-type).

How to use Timolol Ophthalmic drops?

Carefully follow all the instructions on your prescription label, and ask the doctor or pharmacist to explain any part you do not understand. Use this drug exactly as directed.

Timolol control glaucoma but do not cure it. Continue to use this drug even if you feel better. Do not stop using timolol without discussing with your doctor.

Before applying gel or eye drops to wash your hands thoroughly with soap and water. If you are using the gel, shake it once and if you are using drops make sure that the dropper is not chipped or cracked. Do not touch the dropper tip against your eye or anything else; It must be kept clean.

Tilt your head back, pull down the lower lid of your eye with the help of your finger to form a pocket. Hold the dropper (tip down) close to the eye without touching it. Squeeze the dropper so that a single drop falls into the eye. If you are using the gel-forming solution, you should push the bottom of the bottle so that a single drop falls out.

Before using this drops, take off your contact lenses, if you are wearing them, Wait at least 15 minutes before you wear them again.

Replace the dropper cap after each use. Do not rinse the dropper.

Regularly use timolol to get the full benefit from it. To help you remember, use it at the same time each day. It is essential to continue using this drug even if you feel better. Most people with glaucoma or high pressure in the eyes do not feel sick.

What are the side effects of Timolol Ophthalmic drops?

The common side effects observed with the use of this drug include burning, stinging upon instillation, itching, tearing, dry eyes, temporary blurred vision, temporary burning, foreign body sensation, headache. If any of these effects remain or worsen, inform your doctor/pharmacist immediately.

Notify your prescriber immediately if you notice any of these unlikely, but serious side effects such as visual disturbances, fatigue, dry mouth, dizziness, behavioral changes and mood disturbances (depression, confusion, hallucinations, anxiety, and memory loss), bradycardia, arrhythmia, hypotension, hypertension, heart block, cardiac failure, worsening of angina pectoris, palpitation, pulmonary edema, edema cold hands and feet.

Get emergency medical assistance if you notice any of these symptoms such as difficulty breathing, respiratory failure, nasal congestion, dyspnea, cough, and upper respiratory infections, slurred speech, confusion, persistent dizziness, fainting.

A severe allergic reaction to this drug is very rare. However, severe allergic reaction symptoms such as rashes, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing may occur. Get emergency medical assistance immediately if you notice any of the above side effects.

This is not a complete record of all possible side effects. Inform your doctor at the earliest, if you notice any of the side effects that are not mentioned in this article.

What are the precautions while using Timolol Ophthalmic drops?

Inform your doctor/pharmacist before using timolol, if you are allergic to it; or if you have other allergies. This drug may also contain some inactive ingredients like benzalkonium chloride that can cause allergic reactions or other problems. Talk to your doctor/pharmacist for more information.

If you are using other topical eye medication along with this drug, instil it at least 10 minutes before or after you instil timolol eye drops or gel-forming solution.

If you have eye surgery or an eye injury or develop an eye infection while using timolol ophthalmic solution, seek advice from your doctor about continuing current timolol bottle.

This drug may blur your vision during treatment. Do not use any machinery or drive a car if you are unable to see clearly.

Avoid timolol if you have certain medical conditions such as lung disease (like asthma, severe chronic obstructive pulmonary disease), irregular heartbeats (like sinus bradycardia, second or third degree AV block), heart disease (like heart failure, cardiogenic shock)

Before using this medication, inform your doctor or pharmacist about your medical history, mainly of kidney disease, liver disease, diabetes, low blood flow to the brain (cerebrovascular insufficiency), hyperthyroidism, muscle weakness disorders, severe allergies.

If you have diabetes, timolol may mask the symptoms of hypoglycemia (sudden fall in blood sugar level) such as fast/pounding heartbeat you would usually feel when you are hypoglycemic. Other symptoms of hypoglycemia such as sweating and dizziness, does not change by this drug.

In pregnancy, this medication should be used only when benefits outweigh the risk. Discuss with your doctor about using this drug safely.

This drug may cross into breast milk and for more information about the safety of drug talk to your doctor.

What are the drug interactions of Timolol Ophthalmic drops?

Timolol may interact with other medications, herbs, or vitamins you may be using. A drug interaction is when a substance changes the way a drug works which can be harmful or hinder the drug from working well.

Do not start, stop, or alter the dose of the drug without discussing your doctor because your doctor may be monitoring you for possible drug interactions.


Timolol along with other oral beta-blockers (atenolol, propranolol, acebutolol and others) potential may cause additive effects.

Calcium channel blockers:

Using timolol with calcium channel blockers may atrioventricular conduction disturbances, left ventricular failure, and hypotension. Avoid using this drug together.

Some products that may interact with timolol include clonidine, certain antidepressants (like SSRIs such as fluoxetine), digoxin, epinephrine, fingolimod, methyldopa, quinidine.


Alike other topically applied ophthalmic drugs, this drug is also absorbed systemically. Potential causes severe respiratory reactions and cardiac reactions, bronchospasm in patients with asthma, cardiac failure, have been reported following ophthalmic administration of timolol.

Before using timolol, inform your doctor about all of your health conditions such as diabetes, chronic obstructive pulmonary disease (COPD), asthma, poor circulation, heart failure or other heart problems, hyperthyroidism.

What are the forms and strengths of Timolol Ophthalmic drops?

Form: Ophthalmic solution
Strengths: 0.25%, 0.5%

Form: Gel forming solution
Strengths: 0.25%, 0.5%

What is the dosage of Timolol Ophthalmic drops?

For Ocular Hypertension:

Adult (18 and above):

Ophthalmic solution:

Instil one drop in the affected eye every 12 hours 0.25%, if not effective increase to 0.5% one drop every 12 hours. Decrease to one drop/day if ocular hypertension controlled.

Gel-forming solution:

Instil one drop per day in the affected eye.

Children (below 2 years):

Avoid use of this drug in children below two years of age, as the studies have not been established yet.

Children (above 2 years):

Instil one drop in the affected eye every 12 hours 0.25%, if not effective increase to 0.5% one drop every 12 hours. Decrease to one drop/day if ocular hypertension controlled.

Most common questions asked about Timolol Ophthalmic drops / Q&A’s:

What do Timolol ophthalmic drops do to the eye?

Timolol ophthalmic drops/gel is used for the treatment of glaucoma, a condition in which intra-ocular (inside eye) pressure increases, which can lead to gradual vision loss. Timolol is in a class of medications known as beta-blockers. It works by reducing the intra-ocular pressure.


TheMedPharma has made every effort to make sure that all the information is factually correct, comprehensive, and up-to-date. However, this website should not be considered as a substitute for the advice, knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or licensed health care professional before taking any medication. The drug information contained herein is subjected to changes if required. The lack of warnings or other information for a given drug does not mean that the drug or its combination is safe, effective or appropriate for use in all patients.