GENERIC NAME: Rosuvastatin

COMMON BRANDS: Crestor, Rosulip, Camber, Restat, Rosuvatin, Rosunax, Rosuvas

Rosuvastatin is an oral prescription drug, which comes under the class HMG CoA reductase inhibitor or “statins.” It comes as an oral tablet form. Rosuvastatin is available by the brand-name Crestor. It is also available in pharmacies as a generic medicine. In some cases, they may not be available in all strengths or forms as the brand name drug. This drug can be used as part of combination therapy. This means you may need to take it with other medicines.

What is Rosuvastatin used for?

Rosuvastatin is used along with proper nutrition to help lower “bad” cholesterol or fat such as LDL, triglycerides and increase “good” cholesterol such as HDL in the blood. It refers to a group of drugs known as “statins.” It acts by reducing the amount of cholesterol produced by the liver. Reducing “bad” cholesterol and triglycerides and increasing “good” cholesterol reduces the risk of heart disease and helps to limit chances of strokes and heart attacks.

In addition to consuming proper nutrition such as low cholesterol or low-fat nutrition, other lifestyle modifications that may help this medication act better include regular exercise, losing weight if overweight, and quitting smoking. Talk to your doctor for further information.

How to use Rosuvastatin?

Read the Patient Information Leaflet thoroughly if accessible from your pharmacist before you begin using rosuvastatin and any time you get a refill. In case of any queries, talk to your doctor or pharmacist.

Take this medication by orally with or without meals as advised by your doctor, usually once a day.

The dosage depends on your medical condition, response to treatment, age, race, and other drugs you may be taking. Remember to inform your doctor and pharmacist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. If you are of Asian origin, your doctor may advise you to begin with a lower dose because you may be sensitive to its effects.

Antacids including aluminium or magnesium can decrease the absorption of this drug. Therefore, if you are using this kind of antacids, take it at least 2 hours after this drug.

Take this medication regularly to benefit the most from it. Do not forget to take it at the same time each day. It is necessary to continue taking this medication despite feeling well. Many people with high cholesterol or triglycerides do not feel ill.

It is essential to continue to obey your doctor’s advice about nutrition and regular exercise. You may take up to 4 weeks before you notice complete health benefit of this medication.

What are the side effects of Rosuvastatin?

Remember that your doctor/physician has prescribed this drug because he or she has found that the benefit to you is higher than the side effects. Many people using this drug do not have severe side effects.

An insignificant number of people using rosuvastatin may have mild memory problems or confusion. If these unusual symptoms occur, notify your doctor.

Rarely, statins may induce or worsen diabetes. Seek help from your doctor about the risks and benefits or any information you need to know.

Inform your doctor immediately if this unlikely but serious side effect occurs like foamy urine

This drug may sometimes cause muscle problems, which can rarely lead to severe conditions called rhabdomyolysis and autoimmune myopathy. Notify your physician as soon as you observe any of these symptoms during treatment and if these symptoms continue even after your doctor stops the use of this drug such as muscle pain/weakness/tenderness (especially with fever or unusual tiredness), signs of kidney problems (such as a change in the quantity of urine).

This medication may sometimes produce liver problems. If you mark any of the following uncommon but serious side effects, inform your doctor right away, symptoms such as yellowing eyes/skin, dark urine, persistent nausea/vomiting, severe stomach/abdominal pain.

A severe allergic reaction to this medicine is very uncommon. However, seek medical help as soon as possible if you notice any symptoms of a severe allergic reaction such as rashes, itching/swelling (especially of the face/tongue/throat), trouble breathing, dizziness.

This is not a full list of complete side effects. If you mark other side effects not listed above, contact your doctor or pharmacist.

What are the precautions while using Rosuvastatin?

Before using rosuvastatin, inform your physician or pharmacist if you are allergic to it, or if you have some other allergies. This product may include certain inactive ingredients, which can produce allergic reactions or other problems. Talk to your pharmacist for more information.

Before using this drug, inform your physician or pharmacist your medical history, especially if you have any liver disease, kidney problems, or alcohol habits.

Before having surgery, notify your doctor or dentist about every product you use including prescription drugs, nonprescription drugs, and herbal products.

Limit alcoholic beverages. Daily use of alcohol may raise your risk for liver problems, primarily when combined with rosuvastatin. Request your doctor or pharmacist for further information.

Older adults may be extra sensitive to the side effects of this drug, particularly muscle problems.

Pregnant women must avoid using this drug. Rosuvastatin may harm the unborn baby. Hence, it is important to prevent pregnancy during this medication. Consult your doctor for further details and ask the use of reliable forms of birth control treatments such as condoms, birth control pills, while taking this drug. If you are pregnant/think you may get pregnant, inform your doctor right away.

This drug passes through breast milk. Because of the potential danger to the baby, breastfeeding while taking this drug is not advised. Ask your doctor before you breastfeed.

What are the drug interactions of Rosuvastatin?

See also How to Use section.

Drug interactions may modify how your medications act or raise your chance of severe side effects. This record does not mention all possible drug interactions. Keep a record of all the products you are using including prescription and nonprescription drugs and herbal products and notify your doctor and pharmacist. Do not start, stop, or alter the dosage of any medicines without your doctor’s consent.

Some products that can interact with this drug include “blood thinners” such as warfarin, gemfibrozil.

Other medications can affect the elimination of rosuvastatin from your body, which may affect rosuvastatin’s mechanism of action, some examples include ledipasvir, sofosbuvir, velpatasvir, voxilaprevir.

Do not consume any red yeast rice products while you are taking rosuvastatin because some red yeast rice product may also contain a statin called “lovastatin.” Taking rosuvastatin and red yeast rice product together can boost your risk of serious muscle and liver problems.

What are the forms and strengths of Rosuvastatin?

Generic: Rosuvastatin
Form: Oral tablet
Strengths: 5mg, 10mg, 20mg, 40mg

Brand: Crestor
Form: Oral tablet
Strengths: 5mg, 10mg, 20mg, 4mg

What is the dosage of Rosuvastatin?

For Heterozygous Familial Hypercholesterolemia:

Pediatric:

Children (8-10 years): 5mg to 10mg orally once per day, safety and efficacy of doses higher than 10mg per day has not been studied yet.

Children (10-17 years): 5mg to 20mg orally once per day, safety and efficacy of doses higher than 20mg per day has not been studied yet.

For Homozygous Familial Hypercholesterolemia:

Pediatric:

Children (7-17 years): 20mg orally once per day.

For Hyperlipidemia (high cholesterol), Hypertriglyceridemia, and Type III Hyperlipoproteinemia:

Adult (18–64 years): Typical dosage is 5–40mg once a day.

Pediatric:

Children (0–17 years): This medication is studied in children, for this reason, it is not recommended in people below 18 years.

Geriatric:

Older adults (65 years and older): If you are an elderly person, you may need a lower dose or a different schedule. As the kidneys of older adults do not work efficiently and the drug may stay for a more extended period in the body, because of the slow elimination process of the drug.

For Heterozygous high Cholesterol (hyperlipidemia):

Adult (18–64 years): Typical dosage range from 5–40 mg once a day.

Pediatric:

Children (10–17 years): Typical dosage range from 5–20 mg once a day.
Children (8–9 years): Typical dosage range from 5–10 mg once a day.
Children (0–7 years): This drug is not studied in young children, for this reason, it should not be given to children under 8 years.

Geriatric:

Older adults (65 years and older):

If you are an elderly person, you may need a lower dose or a different schedule. As the kidneys of older adults do not work efficiently and the drug may stay for a more extended period in the body, because of the slow elimination process of the drug.

For homozygous high cholesterol (hyperlipidemia):

Adult (18–64 years): Typical starting dosage is 20 mg once a day.

Pediatric:

Children (7–17 years): Typical dosage is 20 mg once a day.

Children (0–6 years): This drug is not studied in young children, for this reason, it should not be given to children under 7 years.

Geriatric: 

Older adults (65 years and older):

If you are an elderly person, you may need a lower dose or a different schedule. As the kidneys of older adults do not work efficiently and the drug may stay for a more extended period in the body, because of the slow elimination process of the drug.

For Heart Disease Prevention:

Adult (18–64 years): Typical dosage range from 5–40mg once a day.

Pediatric:

Children (0–17 years): This drug is not studied in young children, for this reason, it should not be given to children under 18 years.

Geriatric:

Older adults (65 years and older):

If you are an elderly person, you may need a lower dose or a different schedule. As the kidneys of older adults do not work efficiently and the drug may stay for a more extended period in the body, because of the slow elimination process of the drug.

Special Cases:

People with Asian Ancestry:

The body may process this drug differently which may lead to high level of this drug in your blood. Your doctor/physician may give you a starting dosage of 5 mg once a day.

Kidney disease can cause your body to eliminate drugs more slowly which results in a higher amount of drug stays in your body for a more extended time. This enhances your risk of side effects. Your doctor/physician will likely give you a starting dosage of 5 mg daily. Your doctor/physician may later increase your dosage to 10 mg daily.

Disclaimer

TheMedPharma has made every effort to make sure that all the information is factually correct, comprehensive, and up-to-date. However, this website should not be considered as a substitute for the advice, knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or licensed health care professional before taking any medication. The drug information contained herein is subjected to changes if required. The lack of warnings or other information for a given drug does not mean that the drug or its combination is safe, effective or appropriate for use in all patients.