GENERIC NAME: Meloxicam

COMMON BRANDS: Mobic, Vivlodex, Qmiiz ODT

Meloxicam is an oral prescription drug belongs to a class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for relief of mild to moderate pain of rheumatoid arthritis and osteoarthritis. It works by inhibiting cyclooxygenase, leading to the inhibition of prostaglandin synthesis. As prostaglandins sensitise pain receptors, inhibition of their synthesis may be associated with the analgesic and antipyretic effects of meloxicam.

Meloxicam is available in different dosage forms like oral tablet, an orally disintegrating tablet, oral capsule and oral suspension. It is available in both brand-name version and generic-name version. The oral tablet is sold under the common brand “Mobic”, and disintegrating tablet is sold under the common brand “Qmiiz ODT”. The generic drugs usually cost less than the brand name version.

What is Meloxicam used for?

This drug is used to reduces pain, swelling, and joint stiffness caused by the following conditions:

Rheumatoid arthritis: It is a condition that causes pain, swelling, and stiffness of the joint.

Osteoarthritis: It is a common chronic joint condition that causes pain, stiffness, and other symptoms.

Juvenile Rheumatoid Arthritis (JRA): This drug is used to relieve the signs and symptoms of pauciarticular juvenile rheumatoid arthritis in children two years and above. Pauciarticular is when four or fewer joints are involved.

How to use Meloxicam?

Read the medication guide carefully given by your pharmacist before you start taking meloxicam and whenever you get a refill. If you have any problem or you do not understand any part, discuss with your doctor or pharmacist.

Take this medication orally, usually once in a day with a full glass of water or as advised by your doctor. Do not lie down wait for at least 10 minutes after taking this drug. To avoid gastrointestinal problems (like stomach upset) take this drug with food, milk or antacid.

Do not change your dose or take it more frequently than directed by your doctor. Pain medication works best if they are used with the first signs of pain. If you wait until your pain worsens, the medicine may not work well.

Swallow the tablet whole; do not chew it or let it melt/dissolve in your mouth. If you are taking liquid form (oral suspension ) shake well just before taking a dose. Measure liquid medicine with the dosing syringe, or with a special dose-measuring spoon or cup.

The dose of the drug in children is based upon their body weight.

Different dosage forms deliver a different amount of medication, do not switch from one form to another form (such as do not switch from capsule form to tablet form and vice-versa).

Inform your doctor if your pain remains or get worst or if you develop any new symptoms.

It may require up to 2 weeks to get the full benefit of this drug. Use this medication regularly to get the most benefit from it. To avoid missing of dose take this drug at the same time each day.

What are the side effects of Meloxicam?

The common side effects observed with the use of this drug are abdominal pain, diarrhoea, stomach upset, nausea, dizziness, headache, itching or rash. If any of these effects remain or get worse, notify your doctor immediately.

This drug rarely causes severe, possibly fatal liver damage and can even lead to liver failure. The symptoms of liver damage are persistent nausea/vomiting, weakness, severe stomach/abdominal pain, dark urine, yellowing eyes/skin. If you notice any of these side effects, stop taking meloxicam and consult your doctor or pharmacist right away.

Get emergency medical assistance if you notice symptoms of GIT bleeding or ulcers such as stomach pain or abdominal pain, black/sticky stools and bloody vomit.

This drug may increase your blood pressure. Consult your doctor if you notice symptoms of extremely high blood pressure like a headache, dizzy spells and nosebleed.

Seek medical assistance promptly, if you notice any severe side effects, like easy bruising/bleeding, hearing changes (like ringing in the ears), mental/mood changes, signs of kidney problems (like change in the amount of urine), stiff neck, vision changes, symptoms of heart failure (like swelling ankles/feet, unusual tiredness).

This document does not include all possible side effects. If you see other side effects not listed above, reach out to your doctor or pharmacist.

What are the precautions while using Meloxicam?

Inform your doctor/pharmacist before taking meloxicam, if you are allergic to it; or if you have other allergies (including aspirin and other NSAIDs like ibuprofen, diclofenac, naproxen etc.). This drug may also contain some inactive ingredients that can cause allergic reactions or other problems. Talk to your doctor/pharmacist for more information.

Inform your doctor/pharmacist about all the products you are using including prescription, non-prescription, vitamins, nutritional supplements, and herbal products.

Before taking meloxicam, discuss with your doctor or pharmacist about your medical history especially of asthma, severe kidney disease, recent heart bypass surgery (CABG), active bleeding/sores in stomach/intestines (ulcer, gastrointestinal bleeding), blood disorders (like anemia), high blood pressure, diabetes, liver disease, nasal polyps, obesity, tobacco use, stroke, swelling of the ankles/feet/hands.

Meloxicam may cause stomach or intestinal bleeding, which can be fatal, older adults are more susceptible to this condition. Regular use of this drug with alcohol and tobacco may increase your chances for stomach bleeding. Restrict the use of alcohol and stop smoking. Consult your doctor/pharmacist for further information.

NSAIDs like meloxicam sometimes can cause kidney problem which is more likely to occur if you have kidney disease or have heart failure, in severe dehydration, or an older adult. To avoid kidney problems take plenty of water. Notify your doctor instantly if you have a change in the amount of urine.

Caution is recommended when using meloxicam for children with a particular type of arthritis like systemic onset juvenile rheumatoid arthritis as they may be at high risk for a severe bleeding/clotting problem (disseminated intravascular coagulation). Get medical assistance right away if children develop sudden bleeding/bruising or bluish skin in the fingers/toes.

Older adults are susceptible to the side effects of this drug especially to stomach bleeding and kidney problems. Therefore, caution is required while using this drug in older adults.

During pregnancy, use this medication only when benefits outweigh the risk and only if prescribed by your doctor. It is not advised to use this drug during pregnancy as it may harm to the fetus and interference with normal delivery/labour.

This drug may pass into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

What are the drug interactions of Meloxicam?

Meloxicam may interact with other medications, herbs, or vitamins you may be using. A drug interaction is when a substance changes the way a drug works which can be harmful or block the drug from working well.

Do not start, stop, or alter the dose of the drug without consulting your doctor because your doctor may be monitoring you for all possible drug interactions.

Some products that may interact with meloxicam are aliskiren, ACE inhibitors (like captopril, lisinopril), angiotensin II receptor blockers (like losartan, valsartan), cidofovir, corticosteroids (like prednisone), or diuretics (like furosemide), ketorolac.

Meloxicam may increase the levels of certain mental health drug like lithium in your body. Symptoms of lithium toxicity include slurred speech and tremors.

Taking “blood thinners” such as dabigatran/enoxaparin/warfarin and anti-platelet drugs such as clopidogrel with meloxicam increases the risk of severe stomach bleeding. If you are using meloxicam oral suspension, tell your doctor if you are using sodium polystyrene sulfonate.

Take advice from your doctor/pharmacist before using any over-the-counter medicine for cold, allergy, or pain. Many over-the-counter medications contain aspirin or other NSAIDs similar to meloxicam (such as mefenamic acid, naproxen, diclofenac, etc.). Taking these products together with meloxicam can increase the concentration of meloxicam in your body which may result in severe side effects. Read the medication label carefully to check if the medicine contains aspirin or any other NSAIDs. However, you should continue using aspirin if you are already using it for the prevention of heart attack or stroke but only on doctor’s advice.

Meloxicam like some other NSAIDs may interfere with specific laboratory tests, giving a false test result. Make sure that laboratory personnel and all your doctors know you use this drug.

WARNINGS:

Heart risk:

Meloxicam may increase the risk of heart problems, such as blood clot, stroke, heart attack or heart failure which can be fatal. The risk may increase if you already have heart disease or have taken meloxicam for an extended period or at high doses.

Coronary artery bypass graft warning:

This drug is contraindicated for the treatment of pain before coronary artery bypass graft (CABG) surgery (heart surgery is done to increase blood flow to the heart). Taking this drug before surgery may increase the risk of heart attack and stroke.

Gastrointestinal:

This drug may increase your risk of stomach problems, like bleeding, or peptic ulcers which can be fatal. These conditions can occur at any time and without any warning signs. If you are above 65 years, you may have a higher chance of developing severe stomach issues.

What are the forms and strengths of Meloxicam?

Brand: Meloxicam
Form: Oral tablet
Strengths: 7.5mg, 15mg

Brand: Mobic
Form: Oral tablet
Strengths: 7.5mg, 15mg

Brand: Qmiiz ODT
Form: Orally disintegrating tablet
Strengths: 7.5mg, 15mg

What is the dosage of Meloxicam?

For Osteoarthritis:

Adult dosage (18 years and older):

Typical starting dosage: Taken 7.5 mg once per day.
Maximum dosage: Taken 15 mg per day.

Children (0–17 years):

Avoid use of this drug in children below 18 years of age, as the studies have not been established.

For Rheumatoid Arthritis:

Adult dosage (18 years and older):

Typical starting dosage: 7.5mg once per day.
Maximum dosage: 15mg per day.

Children (0–17 years):

Avoid use of this drug in children below 18 years of age, as the studies have not been established.

For Juvenile Idiopathic Arthritis (JIA):

Children (2–17 years):

Typical starting dosage: For children weighing 130 lbs. (60 kg): 7.5mg once daily.
Maximum dosage: 7.5mg per day.

Children (0–1 year):

Avoid use of this drug in children below 1 year, as studies have not been established.

Special Considerations:

For people receiving hemodialysis:

The maximum daily dose for people aged 18 years and older and receiving hemodialysis is 7.5 mg per day. This drug isn’t entirely removed in dialysis. Taking a typical dosage of meloxicam while receiving hemodialysis may cause a buildup of the drug in your blood. This could cause worsened side effects.

Most common questions asked about Meloxicam / Q&A’s:

What are the symptoms of Meloxicam overdose?

Meloxicam overdose symptoms may include lack of energy, drowsiness, nausea, vomiting, stomach pain, bloody, black, or tarry stools, vomit that is bloody or looks like coffee grounds, difficulty breathing, seizures and coma. Seek a medical emergency as soon as possible if you experience any of these symptoms.

Disclaimer

TheMedPharma has made every effort to make sure that all the information is factually correct, comprehensive, and up-to-date. However, this website should not be considered as a substitute for the advice, knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or licensed health care professional before taking any medication. The drug information contained herein is subjected to changes if required. The lack of warnings or other information for a given drug does not mean that the drug or its combination is safe, effective or appropriate for use in all patients.