GENERIC NAME: Felodipine

COMMON BRANDS: Plendil, Cabren, Cardioplen XL, Felotens XL, Keloc SR, Neofel XL, Renedil, Vascalpha

Felodipine is an oral prescription drug, belongs to a class of medications known as calcium channel blockers. It works by blocking calcium which reduces arterial blood pressure by widening blood vessels throughout your body thereby reducing peripheral vascular resistance and also increases the supply of blood and oxygen to the heart. This result in less pressure to built up and slow down your heart rate thereby reducing its workload.

Felodipine is available in both brand-name version and generic-name version. Brand name version is available as an extended-release tablet, and sold under the common brand “Plendil”.

What is Felodipine used for?


Felodipine is used to treat hypertension. Low blood pressure prevents strokes, heart attacks, and kidney problems. In addition to taking medicine, lifestyle changes will also help to control your blood pressure.

How to use Felodipine?

Take felodipine tablet orally once a day without food or in case, if stomach upset occurs, take it with a light meal or as directed by your doctor. The dose of the drug is based on your medical condition and response to treatment.

Swallow the whole tablets; do not split, chew, or crush them.

Take felodipine precisely as instructed. Do not alter your dosage or take it more frequently than prescribed by your doctor.

It controls hypertension but does not cure it. Do not discontinue using felodipine without consulting your doctor even if you feel better.

Avoid eating or drinking grapefruit or grapefruit juice while you are using this medicine. Grapefruit juice can make side effects worse.

In the case of angina, this medication must be taken without missing to be effective. It should not be used in the treatment of angina when it occurs. Use other drugs (for example sublingual nitroglycerin) to reduce attacks of chest pain as directed by your doctor/physician. Discuss with your doctor for further information.

Notify your doctor if your health does not improve or if it worsens (for example, your blood pressure remain high or increase, chest pain persists or worsens).

What are the side effects of Felodipine?

The commonly observed side effects with the use of this drug include dizziness or lightheadedness, a headache, flushing, weakness, stomach upset as your body adjusts to the medication. Inform your doctor/pharmacist immediately, If any of these side effects continue or worsen.

Inform your doctor right away if any of these serious side effects occur like fast/irregular heartbeat and swelling of the hands/ankles/feet (edema).

To lower your danger of dizziness and lightheadedness, stand up slowly when rising from a sitting or lying position.

Severe allergic reaction to this drug is uncommon. However, get medical assistance help right away if you notice any symptoms of a severe allergic reaction, severe dizziness, rash, itching/swelling (especially of the face/tongue/throat), trouble breathing.

This is not a full record of all possible side effects. Inform your doctor at the earliest, if you notice any of the side effects that are not mentioned in this article.

What are the precautions while using Felodipine?

Inform your doctor/pharmacist before taking Felodipine, if you are allergic to it; or if you have other allergies. This drug may also contain some inactive ingredients that can cause allergic reactions or other problems. Talk to your doctor/pharmacist for more information.

Inform your doctor/pharmacist about all the products you are using including prescription, non-prescription, vitamins, nutritional supplements, and herbal products.

Notify your doctor if you have or have ever had heart, liver, or kidney disease.

Felodipine may cause dizziness, do not drive, use machinery, or do anything that needs sharpness until you can do it cautiously. Limit use of alcoholic beverages. Speak to your doctor if you are using marijuana.

If you are undergoing any surgery, including dental surgery, inform your doctor that you are taking felodipine.

Older adults may be more likely susceptible to the side effects of this drug, mainly dizziness and swelling of ankles/feet.

This drug can cause mild swelling of your gums, which may be avoided with good dental hygiene. Properly brush and floss your teeth and visit the dentist if needed.

This medication should be used only if needed during pregnancy and for more information about the safety of drug talk to your doctor.

This drug crosses into breast milk and may have undesirable effects on a nursing infant. Discuss with your doctor before breastfeeding.

What are the drug interactions of Felodipine?

Felodipine may interact with other medications, herbs, or vitamins you may be using. A drug interaction is when a substance changes the way a drug works which can be harmful or hinder the drug from working well.

Do not start, stop, or alter the dose of the drug without discussing your doctor because your doctor may be monitoring you for possible drug interactions.

Grapefruit may interact with this drug and lead to more side effects. Discuss with your doctor before taking grapefruit with this drug.

This drug mainly metabolized by CYP3A4 enzyme. Some medications like ketoconazole, itraconazole, erythromycin, cimetidine inhibit CYP3A4 which result in high levels of felodipine in blood and more side effects.

Some anticonvulsant drugs like phenytoin, carbamazepine, or phenobarbital may interact with this drug and decrease its effectiveness. Alternative antihypertensive drug therapy should be used in these people.

NSAIDs (such as ibuprofen, naproxen), a nasal decongestant (such as phenylephrine, pseudoephedrine), cough-and-cold products, may decrease the effectiveness of felodipine.

This is not a full record of all possible drug interactions, and other drugs may interact with felodipine.

What are the forms and strengths of Felodipine?

Form: Oral extended release tablet
Strengths: 2.5mg, 5mg, 10mg

What is the dosage of Felodipine?

For Hypertension (high blood pressure):

Adult (18 to 64 years):

Initial dose: Take 2.5-5mg orally once a day. The dose is adjusted according to patient response, and if the needed dose is increased at intervals of at least two weeks.

Maintenance dose: Take 2.5-10mg orally once a day.

Maximum dose: Up to 20mg/day.


Children (0 to 17 years):

Initial dose: Take 2.5mg orally once a day. The dose should not exceed more than 10mg.

Geriatric (65 years and older):

Initial dose: Take 2.5mg orally once a day. The dose is adjusted according to patient response, and if the needed dose is increased at intervals of at least two weeks.

Maximum dose: Up to 10mg/day.

Special Dosage Considerations:

Hepatic impairment and renal impairment:

Felodipine is mainly metabolized in the liver, and kidney dosage reduction is recommended for patients with severe hepatic impairment, or patients with hepatic disease and renal failure.

Most common questions asked about Felodipine / Q&A’s:

What are the serious side effects of Felodipine?

Some of the serious side effects of Felodipine may include swelling of the face/eyes/lips/tongue/arms/legs, difficulty breathing or swallowing, fainting, rashes. Seek a medical emergency as soon as possible if you experience any of these effects.


TheMedPharma has made every effort to make sure that all the information is factually correct, comprehensive, and up-to-date. However, this website should not be considered as a substitute for the advice, knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or licensed health care professional before taking any medication. The drug information contained herein is subjected to changes if required. The lack of warnings or other information for a given drug does not mean that the drug or its combination is safe, effective or appropriate for use in all patients.