GENERIC NAME: Clonazepam

COMMON BRANDS: Klonopin, Klonopin Wafer

Clonazepam oral tablet is a prescription drug, belongs to a class of drug known as benzodiazepine which is available with the brand name Klonopin. It is a controlled medicine. It is also available as a generic drug in pharmacies. Generic drugs cost less. In few cases, It may not be available in every strength or form as the brand name version.

What is Clonazepam used for?

This drug is used to prevent and control seizures. It is also known as the anticonvulsant or antiepileptic drug. It is also prescribed in the treatment of panic attacks. Clonazepam acts by calming your brain and nerves.

How to use Clonazepam?

Read the Medication Guide carefully provided by your pharmacist before you start taking clonazepam and every time you get a refill. In case, you have any query, ask your doctor/physician/pharmacist.

Take this medication orally as directed by your doctor/physician, usually 2 or 3 times daily.

Dosage depends on your medical condition, age, and response to treatment. In children, the dose is based on body weight. In older adults, the dose usually starts at a lower dose to minimize the risk of side effects. Do not modify or increase your dose or take it frequently, or take it for a longer duration than instructed by doctor/physician.

Take this medication without missing to benefit the most from it. Take this medicine at the same times each day to avoid confusion and missing the dose. Do not discontinue this medication without informing your doctor/physician. Few conditions may become worse when this drug is abruptly stopped. Your dose needs to be gradually decreased.

This medicine may cause withdrawal reactions if it has been used frequently for a long time or at high doses. In such cases, withdrawal symptoms like seizures, mental/mood changes, shaking, stomach/muscle cramps may occur if you suddenly stop taking this drug. To avoid withdrawal reactions, your doctor/physician may decrease your dose gradually. Seek advice from your doctor/physician/pharmacist for further details, and notify any withdrawal reactions immediately.

When this drug is used for the longer duration, it may not work well. Inform to your doctor/physician if this medication does not work well.

This medication may sometimes cause addiction. The risk of addiction may be higher in case of over-use or addiction to drugs/alcohol. Take this drug as prescribed to lessen the risk of addiction. Seek advice from your doctor/physician/pharmacist for more details.

If you have many different types of seizure disorders, you may experience a worsening of seizures when you initially start using clonazepam. Consult your doctor/physician as soon as possible if this occurs. Your doctor/physician may need to add or modify the dose of your other medications to regulate the seizures.

Notify your doctor if your condition continues or worsens.

What are the side effects of Clonazepam?

Dizziness, nausea, drowsiness, anxiety, trouble sleeping, loss of appetite, sweating, tiredness, or yawning may occur. If any of these above effects continue or worsen, inform your doctor/physician immediately.

Remember that your doctor/physician has prescribed this medicine because your doctor/physician has found that the benefits are higher than the risk of side effects. Several people using this medication do not have severe side effects.

Few people who take anticonvulsants for any condition (like bipolar disorder, seizures, pain) may experience depression, other mental/mood problems, or suicidal thoughts/attempts. Inform your doctor/physician immediately if you notice any of these side effects like unusual/sudden changes in your mood, thoughts, or behavior, memory problems, including confusion, signs of depression, suicidal thoughts/attempts.

Inform your doctor/physician promptly if any of these serious side effects occur like easy bruising/bleeding, signs of infection (like fever, persistent sore throat), slow/shallow breathing.

A severe allergic reaction to this drug is uncommon. However, get medical assistance immediately if you observe any symptoms of a severe allergic reaction such as rash, itching/swelling (especially of the face/tongue/throat), trouble breathing, severe dizziness.

This is not a full record of all possible side effects. If you mark other effects not listed above, contact your doctor/physician/pharmacist.

Also, see warning section.

What are the precautions while using Clonazepam?

Before using clonazepam, inform your doctor/physician/pharmacist if you are allergic to it or other benzodiazepines (like diazepam, lorazepam) or if you have any other allergies. This medication may contain inactive ingredients, which can cause allergic reactions or other problems. Speak to your pharmacist for further details.

Inform your doctor/physician/pharmacist about your medical history before taking this drug mainly of a particular type of eye problem (narrow-angle glaucoma), a specific blood disorder (porphyria), kidney disease, liver disease, lung/breathing problems, mental/mood problems (like depression, thoughts of suicide), personal or family history of overuse or addiction to drugs/alcohol.

This medicine may cause dizziness or drowsiness. Alcohol or marijuana can cause more dizziness or drowsiness. Avoid driving, or using machinery, or doing anything that requires alertness or clear vision till you can do it safely. Avoid alcoholic beverages. Inform your doctor if you are taking marijuana.

Before surgery, inform your doctor/dentist about all the products you are using (including prescription drugs, nonprescription drugs, and herbal products).

In children, the long-term effects of this drug are unknown on physical and mental/ behavioral development and might not be seen until after many years. Therefore, discuss the risks and benefits of clonazepam treatment with your doctor/physician.

Older adults are more prone to the side effects of this drug, mainly drowsiness, and confusion. These side effects can raise the risk of falling.

During pregnancy, this medicine should be used only when needed. It may harm the fetus. However, untreated seizures are a serious condition that can harm both a pregnant woman and her unborn baby, do not stop taking this drug unless advised by your doctor/physician. If you are planning a pregnancy, become pregnant, or think you may be pregnant, right away discuss with your doctor/physician about the benefits and risks of using this medication at the time of pregnancy.

Clonazepam passes into breast milk, and the effect on a nursing infant is unknown. Seek advice from your doctor/physician before breastfeeding.

What are the drug interactions of Clonazepam?

Drug interactions may alter how your drug works or may enhance your risk for serious side effects. This list does not consist of all possible drug interactions. Keep a record of all the products you are using including prescription/nonprescription drugs and herbal products and inform your doctor/ pharmacist. Don’t start, stop, or alter the dosage of any medicines without your doctor/physician’s consent. This medication may interact with some products like orlistat, sodium oxybate.

The risk of severe side effects (like slow/shallow breathing, severe dizziness/drowsiness) may be enhanced if this drug is taken with other products that may also cause drowsiness or breathing problems. Inform your doctor/physician/pharmacist if you are taking other products like opioid pain or cough relievers (like codeine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (like alprazolam, lorazepam, zolpidem), muscle relaxants (like carisoprodol, cyclobenzaprine), or antihistamines (like cetirizine, diphenhydramine).

Read the labels carefully on all your medicines (like an allergy or a cough and cold products) as they may contain ingredients that may cause drowsiness. Seek advice from your pharmacist about using those products safely.

WARNINGS:

Taking clonazepam with opioid medications (like codeine, hydrocodone) may increase your risk of severe side effects, including death. To lessen your risk, your doctor/physician may prescribe you the lowest dose for a shorter duration. Seek medical assistance promptly if any of these severe side effects occur like slow/shallow breathing, severe drowsiness/dizziness, unusual lightheadedness, difficulty waking up.

What are the forms and strengths of Clonazepam?

Form: Oral dispersible tablet
Strengths: 0.125mg, 0.25mg, 0.5mg, 1mg and 2mg.

Form: Oral tablet
Strengths: 0.5mg, 1mg and 2mg.

What is the dosage of Clonazepam?

Adults:

For panic disorder:

0.25mg orally every 12 hours initially; may increase to 1mg/day after 3 days (may increase up to 4mg/day in some patients).

For seizure disorders:

1.5mg/day orally divided every 8 hours; increase by 0.5-1mg every 3 days until the desired effect achieved; not to exceed 20mg/day.

Maintenance for seizures in adults:

2-8mg orally; not to exceed 20mg/day.

Discontinuation of treatment (seizures in adults):

Remove medication gradually over time; decrease the dose once every 3 days by 0.125mg orally every 12 hours until the drug is completely removed.

Pediatric:

For seizure disorders:

Children (under 6 years):

Potential toxic dose:

0.05mg/kg.

Children (under 10 years/below 30kg):

0.01-0.03mg/kg/day orally divided every 8 hours; increase by 0.25-0.5mg/day every 3 days to maximum dose of 0.1-0.2mg/kg/day orally divided every 8 hours.

Maintenance dose:

0.1-0.2mg per kg per day orally divided every 8 hours; not to exceed 0.2mg/ kg/day.

Children (under 10 years/over 30kg):

1.5mg/day orally divided every 8 hours; increase by 0.5-1mg every 3 days until the desired effect achieved; not to exceed 20mg/day.

Maintenance dose:

2-8mg orally; not to exceed 20mg/day.

Discontinuation of the treatment (seizures in children):

Children (below 10 years):

Treatment must be stopped gradually over time, as needed.

Children (10 years and older):

Remove treatment gradually over time; decrease the dose every 3 days by 0.125 mg orally every 12 hours until completely removed.

Dose Modification:

Renal impairment: Supplemental dose in hemodialysis is not required.

Most common questions asked about Clonazepam / Q&A’s

What are the symptoms of Clonazepam overdose?

Clonazepam overdose symptoms may include drowsiness, confusion and coma. Seek a medical emergency as soon as possible if you experience any of these symptoms.

Disclaimer

TheMedPharma has made every effort to make sure that all the information is factually correct, comprehensive, and up-to-date. However, this website should not be considered as a substitute for the advice, knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or licensed health care professional before taking any medication. The drug information contained herein is subjected to changes if required. The lack of warnings or other information for a given drug does not mean that the drug or its combination is safe, effective or appropriate for use in all patients.