GENERIC NAME: Amlodipine

COMMON BRANDS: Norvasc, Amlostin, Istin, Amlo, Amlopres

It is an oral prescription medication used alone or in combination with other medicines for the treatment of high blood pressure. Lowering high blood pressure prevents strokes, heart attacks, and kidney problems. Amlodipine comes under a class of drugs called “calcium channel blockers” and sold under the brand name “Norvasc”. It works by promoting smooth and easy blood flow by dilating blood vessels.

What are the uses of Amlodipine?

Amlodipine is taken alone or in combination with other medications to treat high blood pressure. Lowering high blood pressure prevents strokes, heart attacks, and kidney problems. Amlodipine comes under a class of drugs called as calcium channel blockers. It acts by dilating blood vessels resulting in smooth and easy blood flow.

Amlodipine is also used to stop certain types of chest pain (for example angina). It may also increase your ability to exercise and limit the frequency of angina attacks. It should be avoided to treat attacks of chest pain when they happen. Use other medications (for example sublingual nitroglycerin) to reduce attacks of chest pain as directed by your doctor/physician.

How to use Amlodipine?

Take this medication orally with or without meals as instructed by your doctor/physician, typically once a day.

The dosage depends on your medical examination and response to treatment. Your doctor/physician may slowly increase your dose. Obey your doctor’s directions correctly.

Use this medication without missing to get the most benefit. To remember, take it at the same time every day. It is crucial to continue taking this medication even if you feel better. Most of the people with high blood pressure do not feel ill.

In the case of angina, this medication must be taken without missing to be effective. It should not be used in the treatment of angina when it occurs. Use other drugs (for example sublingual nitroglycerin) to reduce attacks of chest pain as directed by your doctor/physician. Seek advice from your doctor/physician/pharmacist for further information.

Notify your doctor if your health does not improve or if it worsens (for example, your blood pressure remain high or increase, chest pain persists or worsens).

What are the side effects of Amlodipine?

Dizziness, swelling ankles/feet, or flushing, lightheadedness can occur. Inform your doctor/physician/pharmacist immediately, If any of these side effects continue or worsen.

To lower your danger of dizziness and lightheadedness, stand up slowly when rising from a sitting or lying position.

Remember that your doctor/physician has prescribed this medication because he or she has found that the benefits to you are more than the side effects. Most of the people using this medication do not have severe side effects.

Notify your doctor/physician right away if any of these serious side effects occur like a fast/irregular/pounding heartbeat, fainting.

Although this medication is helpful to counter chest pain (for example angina), some people who already have severe heart problems may rarely develop worsening chest pain or a heart attack after beginning this medication or increasing the dose. Seek medical assistance promptly if you observe signs of a heart attack (such as jaw/chest/left arm pain, breathlessness, unusual sweating), worsening chest pain.

Severe allergic reaction to this drug is uncommon. However, get medical assistance help right away if you notice any symptoms of a severe allergic reaction, severe dizziness, rash, itching/swelling (especially of the face/tongue/throat), trouble breathing.

This is not a full record of all possible side effects. If you observe other side effects not listed above, contact your doctor/physician/pharmacist.

What are the precautions while using Amlodipine?

Before using, inform your doctor/physician/pharmacist if you have an allergy to amlodipine or dihydropyridine calcium channel blockers (such as nifedipine, nisoldipine) or if you have any other allergies. This product may also consist of some inactive ingredients, which can induce allergic reactions or other problems. Talk to your pharmacist for further details.

Before using this medication, tell your doctor/physician/pharmacist about your medical history, particularly like a certain heart problem (for example aortic stenosis), liver disease, very low blood pressure.

Amlodipine may cause dizziness, do not drive, use machinery, or do anything that needs sharpness until you can do it cautiously. Limit use of alcoholic beverages. Speak to your doctor if you are using marijuana.

Before having surgery, tell your doctor/dentist about all the products may be using (for example prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more likely susceptible to the side effects of this drug, mainly dizziness.

This medication should be used only if needed during pregnancy. Discuss the dangers and benefits with your doctor/physician.

This drug passes into breast milk. Consult your doctor/physician before breastfeeding.

What are the drug Interactions of Amlodipine?

Drug interactions may alter how your medications act or increase your chance for severe side effects. This record does not include the full list of all possible drug interactions. Have a record of all the products you are using (for example prescription/nonprescription drugs and any herbal products) and give it to your doctor/physician and pharmacist. Do not start, stop, or adjust the dosage of any medicines without your doctor’s consent.

Some products may have some ingredients that could increase your blood pressure. Tell your doctor/physician/pharmacist about the products you are using, and ask how to use them safely (especially cough and cold products, NSAIDs or diet aids like ibuprofen/naproxen).

What are the forms and strengths of Amlodipine?

Form: Oral tablets
Strengths: 2.5 mg, 5 mg, 10 mg

What is the dosage of Amlodipine?

For Hypertension (high blood pressure):

Adults

5mg per day orally initially; may be increased by 2.5mg per day every 7-14 days (not to exceed 10mg/day orally; maintenance: 5-10mg/day orally).

Pediatric

Children below 6 years: Safety and efficacy not established.
Children 6 years and older: 2.5-5mg per day orally.

Geriatric

2.5-5mg per day orally initially, may be increased by 2.5mg per day every 7-14 days; not to exceed 10 mg per day orally; maintenance: 5-10mg per day orally.

For Coronary Artery Disease:

Treatment of vasospastic angina (Prinzmetal or variant angina) or chronic stable angina documented coronary artery disease (CAD) in patients without heart failure less than 40%.

Adult

5-10mg per day orally initially; maintenance is 10mg per day orally.

Geriatric

2.5-10mg per day orally initially; maintenance is 10mg per day orally.

For Angina:

Adult

5-10mg per day orally; maintenance is 10 mg per day orally.

Geriatric

2.5-10mg per day orally; maintenance: 10 mg per day.

Dosage Modifications:

Hepatic insufficiency, consider starting with 2.5mg per day orally.

Severe hepatic impairment: Titrate slowly.

Dosing Considerations:

Also given in combination with benazepril (Lotrel), olmesartan (Azor), telmisartan (Twynsta), atorvastatin (Caduet), and valsartan (Exforge).

Geriatric

Start at low dose end of dosing range; elderly patients have more frequency of decreased renal, hepatic or cardiac function.

Most common questions asked about Amlodipine / Q&A’s:

What are the symptoms of Amlodipine overdose?

Amlodipine overdose symptoms may include dizziness, fainting and rapid heartbeat. Seek a medical emergency as soon as possible if you experience any of these symptoms.

Disclaimer

TheMedPharma has made every effort to make sure that all the information is factually correct, comprehensive, and up-to-date. However, this website should not be considered as a substitute for the advice, knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or licensed health care professional before taking any medication. The drug information contained herein is subjected to changes if required. The lack of warnings or other information for a given drug does not mean that the drug or its combination is safe, effective or appropriate for use in all patients.